Drug discovery researchers today have strongly emphasized the importance of obtaining qualitative measurements of their ëdrug candidatesî as early as possible in the discovery process.   Accelerated evaluation is ìthe name of the gameî in everything from understanding basic ADME/Tox tendencies to determining biotransformation ìhot-spotsî to complete structure determination.  Samples from both in-vitro and in-vivo origin can be analyzed.  Novatiaís metabolism approach encompasses four basic steps which can be mixed and matched to address your specific project needs:

• Novatia's approach begins with compound Characterization to determine pre-assay integrity and assess compound performance for all downstream metabolic assays.
  
  
  
• During Screening, Novatia offers various high-throughput assays such as Metabolic Stability and Half-Life Determination.
  
  
  
• More detailed metabolite information can be obtained using our Profiling services. Offerings range from in-vitro inter-species metabolic profiles to in-vivo metabolite identification.
  
  
  
• And finally, highly detailed structural information can be obtained using our Elucidation services. Novatia utilizes multi-stage MS/MS, high resolution MS and high-field capillary NMR to answer questions such as site of attachment and even complete structural assignment.