About Us

History and Intro

Bio Info

Expertise

Expertise

Core areas of expertise:

  • LC/MS and LC/MS/MS applications in the pharamaceutical industry
  • LC/MS and MS/MS instrumentation development
  • NMR applications for pharmaceutical research
  • NMR methods development of high througput methods
  • systems integration
  • biomolecule analysis using mass spectrometry
    • intact molecular weight analysis of biomolecules 
    • heterogeneity profiling
    • post-translational modifications
    • protein identification and sequencing
    • SEQUEST database searching
    • sample handling strategies and nano-scale methods (nanoLC and nanospray)
    • methods and expertise for proteomics analyses
  • NMR analysis for industrial research
    • structure elucidation
    • receptor - ligand binding studies using diffusion methods
    • micro-flow NMR using capillary systems
    • selective excitation methods for localized structure determination
    • automated NMR methods development
    • high throughput NMR methods development
    • NMR data management
  • automated LC/MS methodology
    • biomolecules
    • combinatorial chemistry
    • metabolites, impurities, degradants
  • instrumentation
    • triple quadrupole mass spectrometry
    • API (ESI, APcI) ion source development/optimization
    • ion trap mass spectrometry
    • MALDI/MS
    • micro and capillary LC
    • high field multiple resonance multiple dimensional NMR
  • informatics
    • internet/intranet development (If you like our website, you need Manila. We can help you take advantage of this great web publishing tool!)
    • UNIX, Perl, AppleScript, VisualBASIC, TSQ ICL (instrument control language) scripting and programming
    • ThermoFinnigan Xcalibur data system automation through the Xcalibur XDK (e.g., ProMass for Xcalibur)
    • analytical data, sample tracking, and systems integration
    • development of scientific visualization tools
    • web applications for management of scientific data using XML-RPC and SOAP
  • instrument-specific expertise
    • ThermoFinnigan TSQ/SSQ 700/7000 and new: TSQ Quantum, Xcalibur (PC) and ICIS-II (UNIX) data systems
    • ThermoFinnigan ion traps (LCQ Classic, DUO, DECA, XP, Advantage, LTQ)
    • HP LC/MSD
    • PE Biosystems Voyager DE MALDI-ToF systems
    • Varian Unity & Gemini Series NMR Spectrometers

    For more information on real-world examples of our exptertise, check out our Products page, or if you want more information on our background you can read our Bio Info page.

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