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Metabolites

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Metabolite Profiling

It is highly desirable to obtain simultaneous identification of drug metabolites along with component profiling information for inter-species comparisons.  By acquiring the full scan and MS/MS data during an LC/MS run, we are able to propose sites of biotransformation for most major metabolites and relate their relative abundance across samples.  Rather than conduct slow manual interpretation at this stage, we quickly provide this time-sensitive data using our own patented software, MetLabTM Profiler.  This software generates rapid interpretation and reporting of proposed metabolites in an automated fashion.  The goal is to provide you with insight into compound "hot-spots" for all major metabolites in order to assist you in directing your chemistry decisions.

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MetLab Profiler Output Example:

 

MET_Prof_1: Metabolism Profiling Figure 1

Buspirone metabolites found using MetLabTM Profiler

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