Skip to main content

MS Peptide & Protein Pricing

Standard pricing for peptide and protein mass spectral analysis

About Novatia’s peptide and protein analysis
All analyses use electrospray ionization (ESI)
Not sure if you need High Resolution or not? Click here

Protein Analysis

AnalysisSingle SampleBulk priceDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250$225 (25 or more samples in a single submission)LCMS is used for all intact protein samples. Normal resolution is used to determine isotopic average masses in a sample. LCMS
LC/MS with sample treatment (see description for options)$300$270 (25 or more samples in a single submission)For the analysis of proteins in general. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) PNGAse F and reduction
1. PNGase_LCMS
2. Reduction_LCMS
3. PNGAse_Reduction_LCMS
High Resolution (HRMS) LC/MS Exact Mass Profiling$350Exact (Monoisotopic) mass can be determined for proteins up to ~25 kD with < 3 ppm mass accuracy.HRMS_LCMS
Peptide Mapping LCMS$1350Detailed peptide mapping to confirm sequence and modifications of a target protein. See sample peptide mapping report.Peptide_Mapping
High-throughput 96 and 384 well plate MS analysisN/AInquire within (priced by the plate)A ballistic gradient and trap column is used to analyze relatively clean intact protein samples.

Peptide Analysis

AnalysisSingle SampleBulk PriceDescriptionExcel Sample Submission Sheet Code
Molecular Weight (MW) Confirmation$100$90 (25 or more samples in a single submission)Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids). MW_Confirmation
High Resolution Flow Injection$150Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids).HRMS
LC/MS Profiling$250$225 (25 or more samples in a single submission)Nominal mass resolution is used to determine isotopic average masses in a sample. LCMS
High Resolution LC/MS Exact Mass Profiling$350 Exact (Monoisotopic) mass can be determined for peptides up to ~25 kD with < 3 ppm mass accuracy.HRMS_LCMS
Peptide Mapping LCMS$1350Detailed peptide mapping to confirm sequence and modifications of a target protein. See sample peptide mapping report.Peptide_Mapping

mAb Analysis

AnalysisSingle SampleBulk priceDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250$225 (25 or more samples in a single submission)LCMS analysis is used to determine MAb average masses and reveals heterogeneity due to attached glycans or other modifications.LCMS
LC/MS with sample treatment (see comments for options)$300$270 (25 or more samples in a single submission)For the analysis of deglycosylated mAbs and/or mAb subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.
1. PNGase_LCMS
2.Reduction_LCMS
3. Fab_Fc_LCMS
Peptide Mapping LCMS$1350Detailed peptide mapping to confirm sequence and modifications of a target mAb. See sample peptide mapping report.Peptide_Mapping
High-throughput 96 and 384 well plate MS analysisN/AInquire within (priced by the plate)A ballistic gradient and trap column is used to analyze relatively clean intact mAb samples.

Antibody Drug Conjugate Analysis

AnalysisSingle SampleBulk PriceDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250$225 (25 or more samples in a single submission)For the analysis of Intact ADCs.LCMS
LC/MS with sample treatment (see description for options)$300$270 (25 or more samples in a single submission)For the analysis of deglycosylated ADCs and/or ADC subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.
1. PNGase_LCMS
2.Reduction_LCMS
3. Fab_Fc_LCMS
LC/MS Profiling and DAR calculation$300$270 (25 or more samples in a single submission)For the analysis of Intact ADCs. Includes DAR (drug-to-antibody ratio) calculation.LCMS_DAR
LC/MS with sample treatment (see description for options) and DAR calculation$350$315 (25 or more samples in a single submission)For the analysis of deglycosylated ADCs and/or ADC subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.

Includes DAR (drug-to-antibody ratio) calculation.
1. PNGase_LCMS
2.Reduction_LCMS
3. Fab_Fc_LCMS
Peptide Mapping LCMS$1350Detailed peptide mapping to confirm sequence and modifications of a target ADC. See sample peptide mapping report.Peptide_Mapping

Pricing policies effective 19-Sep-2018.

ROUTINE ANALYSIS TERMS AND CONDITIONS:

  1. Typical turnaround time is 1-5 business days for most analyses. Rush service moves your submission to the front of the instrument queue for 2X charge. Peptide mapping usually within one week. Nominal mass oligonucleotides and 1D NMR usually same day or next day. Large numbers of samples may take longer.
  2. Payment for services will be made by check, credit card, wire transfer or ACH.  An approved purchase order (Net 30) or credit card details will be provided to Novatia upon submitting an analysis request: http://www.enovatia.com/novatia-sample-submission-form/ When paying by credit card, transactions will process at the time service is provided. Invoices are due and payable within the time noted on the invoice, measured from the date of the invoice.
  3. Work is NOT performed under regulated conditions (e.g. cGxP) and is “for information only.”
  4. Customer represents that submitted samples do not warrant exceptional handling or precautions (e.g., as with radioactive samples, controlled substances, highly potent or cytotoxic compounds, etc.) and that any available safety information (safety data sheet, occupational exposure level, control banding, etc.) will be relayed to Novatia prior to sample shipment.
  5. After analysis, customer will receive an email to view results on Novatia’s Secure Web Portal: Most MS results are ProMass HTML or ACD PDF report;  NMR results include ACD PDF report and zip file of raw NMR data.
  6. If additional custom data interpretation/reporting is required (apart from what is explicitly included in Point 5), Novatia can provide a quote to the customer at our hourly rate of $350/hr.