MS Small Molecule Pricing
Standard pricing for small molecule mass spectral analysis
FAQs
How do I get my Small Molecule MS results and what will they look like?
Results will be delivered by email containing a PDF of the processed data (or report if HRMS_structure or HRMS_LCMS_structure are selected).
Who can I contact with questions about Small Molecule MS services?
Please contact ms@enovatia.com for specific questions about analyses.
How do I know if I need high resolution data?
Visit our article explaining mass accuracy and resolution to help you decide.
What ionization technique do Novatia's methods use?
All routine oligonucleotide methods use electrospray ionization (ESI).
Routine MS Methods for Small Molecule Samples
Method selection can be found under sample type Small Molecule of the Excel sample submission sheet. Confirmation of an expected product, MW determination of major component(s), or overall purity assessment, includes analyst interpretation time.
| Analysis (Excel Sample Submission Sheet Code) | Price Per Analysis | Method Details |
| MW_Confirmation_SmMol | $125 | Purpose: MW confirmation of small molecules with MW < 1500Da.
LC Method: Flow Injection
MS Method: Nominal Mass |
| LCMS | $400 | Purpose: Impurity profiling of small molecules with MW < 1500Da.
LC Method: Run 1: 10 minute gradient; Run 2: 10 minute gradient.
MS Method: Run 1: Nominal Mass, Pos ESI; Run 2: Nominal Mass, Neg ESI |
| LCMS_TEAB | $300 | Purpose: Impurity profiling of NTPs, short oligonucleotides (≤ 3 bases) or phosphoramidites.
LC Method: 20 minute gradient
MS Method: Nominal Mass |
| HRMS_SmMol | $300 | Purpose: MW confirmation of small molecules with MW < 1500Da.
LC Method: Flow Injection
MS Method: High Resolution, Monoisotopic Mass |
| HRMS_LCMS_SmMol | $500 | Purpose: Impurity profiling of small molecules with MW < 1500Da.
LC Method: Run 1: Flow Injection for Ionization confirmation; Run 2: 10 minute gradient.
MS Method: Run 1: Nominal Mass; Run 2: High Resolution, Monoisotopic Mass |
| HRMS_LCMS_SmMol_TEAB | $450 | Purpose: Impurity profiling of NTPs, short oligonucleotides (≤ 3 bases) or phosphoramidites.
LC Method: 20 minute gradient
MS Method: High Resolution, Monoisotopic Mass. |
| HRMS_structure | $750 | Purpose: MW and structure confirmation of a single small molecule target with MW < 1500Da.
LC Method: Flow Injection
MS Method: High Resolution, Monoisotopic Mass, MSn Fragmentation |
| HRMS_LCMS_structure | $1000 | Purpose: MW, structure confirmation, and impurity profiling of a single small molecule target with MW < 1500Da.
LC Method: Run 1: Flow Injection for Ionization confirmation; Run 2: 10 minute gradient.
MS Method: Run 1: Nominal Mass; Run 2: High Resolution, Monoisotopic Mass, MSn Fragmentation |
Custom LCMS Method
Please contact ms@enovatia.com before submitting a custom method request.
| Analysis (Excel Sample Submission Sheet Code) | Description | Price per analysis |
| Custom LCMS Method | Please contact MS@enovatia.com before submitting for this method.
Custom method for LCMS on select molecule types.
Requirements:
1. Requested solvents must be MS compatible. If Novatia does not have requested solvents, submitter must provide them.
2. The column Novatia would typically utilize for a type of sample for routine LCMS will be used by default. Any specific column to be used will need to be provided by the submitter. If the submitter wants the column returned, they will need to select return my samples.
3. Gradient length cannot exceed 2 hours per analysis or 0.4 ml/ min. | $1600 |
Additional Services
| Service | Price
|
| Additional Data Interpretation & Reporting - (Quoted) | $400 / hr |
| Posting of raw MS data | $200 per submission |
| Sample Return | $300 |
| 50-minute training session (see details below) | $400 |
50-minute training session: This service is meant to highlight the data provided in the report and how to view the posted MS or NMR data. This service is not meant to troubleshoot potential sample issues. Beneficial for first time submitters as we will explain the information provided in the data we have posted. If requesting this service, the results notification email sent by the analyst will provide times available to review the posted results. You will need to schedule a time that works best within the next 3 business days from the day the results email is sent. The training session must be completed within 7 business days from the results notification email.
Pricing and policies effective 10-Jul-2025.