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MS Biomolecule Pricing

Standard pricing for biomolecule mass spectral analysis

About Novatia’s oligonucleotide analysis
About Novatia’s peptide and protein analysis
All analyses use ESI unless otherwise requested
Samples requiring APCI will incur an additional charge of $75


Standard Nucleotide Analysis

AnalysisSingle Sample96-well Plate PricingComments
Flow Injection / Molecular Weight Confirmation$75$1200 full plate, $480 + $7.5 x (number of samples) partial plateLowest-cost option for MW confirmation, nominal mass
5 Minute LC/MS Gradient$150$3000 full plate, $480 + $26.25 x (number of samples) partial plateLower-cost option for impurity profiling
20 Minute LC/MS Gradient$250N/ABest for detailed oligonucleotide and NTP impurity profiling applications
Typical turnaround is same day or next day for standard oligonucleotide analyses. 1-5 business days for NTPs.

High Resolution/Accurate Mass (HRMS) Nucleotide Analysis

AnalysisSingle SampleComments
Flow Injection / Exact Mass Determination$150Desalting ESI
LC/MS$350Includes NTPS, PEGylated oligos, or unmodified oligos
Oligonucleotide Sequencing :  MS/MS oligo sequence confirmation for oligos up to 40 bases in length, includes exact mass determination. Includes Microsoft Excel report. Inquire for a more detailed report. $800 per sample.
Oligo metabolite identification :  including incubation in bio matrices (serum, plasma, etc.), sample extraction,  and high-resolution accurate mass analysis to determine metabolites and the rate of disappearance of the parent compound: inquire.    

Peptide and Intact Protein Analysis

AnalysisSingle SampleComments
Flow Injection / Molecular Weight Confirmation$100Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids). Not applicable to proteins.
HRMS Flow Injection$150Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids). Not applicable to proteins.
LC/MS Profiling$250LCMS is used for all intact protein samples. Normal resolution is used to determine isotopic average masses in a sample.
High Resolution LC/MS Exact Mass Profiling$350Exact (Monoisotopic) mass can be determined for peptides and proteins up to ~25 kD with < 3 ppm mass accuracy.
Intact Monoclonal Antibody (MAb) LCMS$250LCMS analysis is used to determine MAb average masses and reveals heterogeneity due to attached glycans or other modifications.
Monoclonal Antibody (MAb) LCMS with sample treatment$300For analysis of antibody conjugates, analysis of deglycosylated MAbs before and after conjugation is highly recommended. Sample treatment options include: deglycosylation and/or disulfide reduction.
Peptide Mapping LCMS Inquire Detailed peptide mapping to confirm sequence and modifications of a target protein.
Typical turnaround is 1-5 business days for standard peptide and protein analyses.

All analyses include a ProMass HTML report of results available via secure customer web portal.

Rush service is also available for a 2x charge. Choosing Rush service will move your sample(s) to the front of our analysis queue.

Pricing policies effective 21-July-2017.