NMR Services
Novatia offers a wide variety of solution state NMR services either stand-alone or as part of multidisciplinary group that includes our Pharmaceutical Support and Mass Spectrometry teams.
Nuclear Magnetic Resonance (NMR) is an analytical technique used to study compounds including small molecule pharmaceuticals (active pharmaceutical ingredients), natural products, fine chemicals, polymers and biomolecules (including proteins, nucleic acids and carbohydrates) and more. NMR data is mostly used to determine the precise arrangement of atoms that make up a molecule either by showing how they are bonded (scalar coupling) or how close they are to each other (dipolar coupling) in space. The application of Mass Spectrometry (MS) and NMR analysis are often the “go-to” methods of chemical and biological researchers when questions of chemical structure arise.
Why Choose Novatia for your NMR Needs?
Routine NMR Analysis
Novatia is equipped with a 500 MHz Bruker Avance III HD with a broad band prodigy cryoprobe and 60 position Samplexpress which allows us to collect to high-quality data on smaller amounts of material in less time on routine analysis such as:
- 1D experiments for 1H, 13C, 19F, 31P
- 2D experiments (HSQC, HMBC, DEPT, COSY, NOESY/ROESY)
- 1D quantitative NMR (qNMR)
Problem Solving NMR Analysis
Novatia’s staff spectroscopists have extensive experience in solving problems with NMR including:
- relative response factor determination
- structure determination / confirmation
- purity & identity testing
- polymer characterization
- biosimilar method characterization and method development
