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MS Peptide & Protein Pricing

Standard pricing for peptide and protein mass spectral analysis

About Novatia’s peptide and protein analysis

FAQs

Who can I contact with questions about peptide/protein MS services?

Please contact ms@enovatia.com for specific questions about analyses.

How do I know if I need high resolution data?

Visit our article explaining mass accuracy and resolution to help you decide.

What ionization technique do Novatia's methods use?

All routine oligonucleotide methods use electrospray ionization (ESI).

Routine LCMS Methods for Protein Samples

Method selections can be found under sample(s) type peptide, PNA, protein, mAb or Antibody_Drug_Conjugate of the Excel sample submission sheet.
Excel sample submission sheet codePrice Per AnalysisMethod DetailsSample Treatment Done by NovatiaControl/Additional Information needed
MW_confirmation_peptide$100Sample type: peptides or PNAs
LC method: desalting only
MS method: average mass
n/an/a
HRMS$150Sample type: <32 kDa peptides or PNAs
LC method: desalting only
MS method: high resolution, monoisotopic mass
n/an/a
LCMS_P$275Sample type: peptides, proteins, PNAs, or mAbs
LC method: 10-minute gradient
MS method: average mass
n/an/a
HRMS_LCMS$350Sample type: <32 kDa peptides, proteins, or PNAs
LC method: 10-minute gradient
MS method: high resolution, monoisotopic mass
n/an/a
PNGase_LCMS$325Sample type: protein or mAb
LC method: 10-minute gradient
MS method: average mass
Deglycosylationn/a
Reduction_LCMS$325Sample type: protein or mAb
LC method: 10-minute gradient
MS method: average mass
Reductionn/a
PNGase_Reduction_LCMS$325Sample type: protein or mab
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, Reductionn/a
Fab_Fc_LCMS$325Sample type: mAb
LC method: 10-minute gradient
MS method: average mass
Fab Fc digestionMust provide HC sequence
PNGase_Fab_Fc_LCMS$325Sample type: mAb
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, Fab Fc digestionMust provide HC sequence
Reduction_Fab_Fc_LCMS$325Sample type: mAb
LC method: 10-minute gradient
MS method: average mass
Reduction, Fab Fc digestionMust provide HC sequence
PNGase_Reduction_Fab_Fc_LCMS$325Sample type: mAb
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, Reduction, Fab Fc digestionMust provide HC sequence
Peptide_Mapping$1500Sample type: peptide, protein, or mAb
LC method: 1-hour gradient
MS method: high resolution, monoisotopic mass
Trypsin digest, disulfide reductionMust provide sequence
Peptide_Mapping_disulfides$3000Sample type: protein or mAb
LC method: 1-hour gradient
MS method: high resolution, monoisotopic mass
Trypsin digestMust provide sequence
Native_LCMS$400Sample type: intact mAb/mAb subunit
LC method: 14-minute SEC run with native buffers
MS method: average mass
n/an/a
Native_PNGase_LCMS$475Sample type: intact mAb/mAb subunit
LC method: 14-minute SEC run with native buffers
MS method: average mass
Deglycosylationn/a
Native_LCMS_DAR$450Sample type: ADC
LC method: 14-minute SEC run with native buffers
MS method: average mass
n/aProvide conjugate mass, must submit unmodified mAb for control analysis by Native_LCMS
Native_PNGase_LCMS_DAR$500Sample type: ADC
LC method: 14-minute SEC run with native buffers
MS method: average mass
DeglycosylationProvide conjugate mass, must submit unmodified mAb for control analysis by Native_PNGase_LCMS
LCMS_DAR$325Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
n/aProvide conjugate mass, must submit unmodified mAb for control analysis by LCMS_P
PNGase_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
DeglycosylationProvide conjugate mass, must submit unmodified mAb for control analysis by PNGase_LCMS
Reduction_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
ReductionProvide conjugate mass, must submit unmodified mAb for control analysis by Reduction_LCMS
PNGase_Reduction_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, ReductionProvide conjugate mass, must submit unmodified mAb for control analysis by PNGase_Reduction_LCMS
Fab_Fc_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
Fab Fc digestionProvide conjugate mass, HC sequence, and must submit unmodified mAb control for analysis by Fab_Fc_LCMS
PNGase_Fab_Fc_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, Fab Fc digestionProvide conjugate mass, HC sequence, and must submit unmodified mAb control for analysis by PNGase_Fab_Fc_LCMS
PNGase_Reduction_Fab_Fc_LCMS_DAR$375Sample type: ADC
LC method: 10-minute gradient
MS method: average mass
Deglycosylation, Reduction, Fab Fc digestionProvide conjugate mass, HC sequence, and must submit unmodified mAb control for analysis by PNGase_Reduction_Fab_Fc_LCMS

Additional Services

ServicePrice
Additional Data Interpretation & Reporting - (Quoted)$400 / hr
Posting of raw MS data$200 per submission
Sample Return$300
50-minute training session (see details below)$400

Pricing and policies effective 10-Jul-2025.