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MS Peptide & Protein Pricing

Standard pricing for peptide and protein mass spectral analysis

About Novatia’s peptide and protein analysis
All analyses use ESI unless otherwise requested
Samples requiring APCI will incur an additional charge of $75

 

Protein Analysis

AnalysisSingle SampleDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250LCMS is used for all intact protein samples. Normal resolution is used to determine isotopic average masses in a sample. LCMS
High Resolution (HRMS) LC/MS Exact Mass Profiling$350Exact (Monoisotopic) mass can be determined for proteins up to ~25 kD with < 3 ppm mass accuracy.HRMS_LCMS
Peptide Mapping LCMS Inquire
Detailed peptide mapping to confirm sequence and modifications of a target protein.Peptide_Mapping
Typical turnaround is 1-5 business days for standard protein analyses.

Peptide Analysis

AnalysisSingle SampleDescriptionExcel Sample Submission Sheet Code
Molecular Weight (MW) Confirmation$100Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids). MW_Confirmation
High Resolution Flow Injection$150Reasonably pure peptides only. Includes PNAs (peptide-nucleic acids).HRMS
LC/MS Profiling$250Nominal mass resolution is used to determine isotopic average masses in a sample. LCMS
High Resolution LC/MS Exact Mass Profiling$350Exact (Monoisotopic) mass can be determined for peptides up to ~25 kD with < 3 ppm mass accuracy.HRMS_LCMS
Peptide Mapping LCMS Inquire
Detailed peptide mapping to confirm sequence and modifications of a target protein.Peptide_Mapping

mAb Analysis

AnalysisSingle SampleDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250LCMS analysis is used to determine MAb average masses and reveals heterogeneity due to attached glycans or other modifications.LCMS
LC/MS with sample treatment (see comments for options)$300For the analysis of deglycosylated mAbs and/or mAb subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.

1. PNGase_LCMS
2.Reduction_LCMS
3. Fab_Fc_LCMS
Peptide Mapping LCMS Inquire
Detailed peptide mapping to confirm sequence and modifications of a target ADC.Peptide_Mapping

Antibody Drug Conjugate Analysis

AnalysisSingle SampleDescriptionExcel Sample Submission Sheet Code
LC/MS Profiling$250For the analysis of Intact ADCs.LCMS


LC/MS with sample treatment (see description for options)
$300For the analysis of deglycosylated ADCs and/or ADC subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.



1. PNGase_LCMS
2. Reduction_LCMS
3. Fab_Fc_LCMS
LC/MS Profiling and DAR calculation$300For the analysis of Intact ADCs. Includes DAR (drug-to-antibody ratio) calculation.LCMS_DAR


LC/MS with sample treatment (see description for options) and DAR calculation
$350For the analysis of deglycosylated ADCs and/or ADC subunits. Sample treatment options include:
1) Deglycosylation by PNGase F
2) Disulfide reduction
3) Fab and Fc fragmentation
or any combination of the 3.
Includes DAR (drug-to-antibody ratio) calculation.



1. PNGase_LCMS
2. Reduction_LCMS
3. Fab_Fc_LCMS
Peptide Mapping LCMS Inquire
Detailed peptide mapping to confirm sequence and modifications of a target ADC.Peptide_Mapping

All analyses include a ProMass HTML report of results available via secure customer web portal.

Rush service is also available for a 2x charge. Choosing Rush service will move your sample(s) to the front of our analysis queue.

Pricing policies effective 19-Sep-2018.